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Jeevan Prasain, PhD

Jeevan Prasain, PhD
Assistant Professor
Department of Pharmacology and Toxicology
1918 18th Street South
McCallum Building Room 456
Birmingham, AL 35294-0005
Phone: (205) 996-2612
Fax: (205) 934-6944


B.Sc. in Chemistry, Tribhuvan University, Nepal; M.Sc. in Chemistry, Tribhuvan University, Nepal; Ph.D. in Pharmaceutical Chemistry, Toyama Medical & Pharmaceutical University, Japan; Postdoctoral Fellow in Protein Chemistry, Biotechnology Research Institute, Montreal, Canada; Postdoctoral Fellow in Antibiotics Research, Inst. Phys. Chem Res., Japan; Postdoctoral Fellow in Botanicals/LC-MS at the University of Alabama at Birmingham

Research/Clinical Interest

Metabolism and bioavailability of polyphenols, identification of bioactive novel natural products from microorganisms, mass spectrometric analysis of small molecules in biological samples.

Selected Publications

  1. Prasain J.K., Wang C.-C., Barnes S. Mass spectrometric analysis of flavonoids in biological samples. Free Radical Biology & Medicine, 37: 1324-1350, 2004
  2. Prasain, J.K., Jones, K., Brissie, N., Moore, D.R. II, Wyss, J.M., Barnes, S. Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry. Journal of Agricultural Food Chemistry 52: 3708-3712, 2004.
  3. D'Alessandro T. Prasain J. Benton MR. Botting N. Moore R. Darley-Usmar V. Patel R. Barnes S. Polyphenols, inflammatory response, and cancer prevention: chlorination of isoflavones by human neutrophils. Journal of Nutrition. 133(11 Suppl 1):3773S-3777S, 2003.
  4. Prasain, J.K., Jones, K., Kirk, M., Wilson, L., Smith-Johnson, M., Weaver, C.M., Barnes, S. Identification and quantitation of isoflavonoids in Kudzu Dietary Supplements by HPLC and electrospray ionization tandem mass spectrometry. Journal of Agricultural Food Chemistry, 51:4213-4218, 2003.
  5. Prasain JK. Patel R. Kirk M. Wilson L. Botting N. Darley-Usmar VM. Barnes S. Mass spectrometric methods for the analysis of chlorinated and nitrated isoflavonoids: a novel class of biological metabolites. Journal of Mass Spectrometry. 38:764-771, 2003.