Division of Preventive Medicine
Medical Towers 619
1717 11th Avenue South
Birmingham, Alabama 35205
Dr. Shikany’s research interests include the association between diet and the epidemiology and prevention of chronic disease (including cancer and cardiovascular disease), with special emphasis on antioxidants, dietary fats, glycemic index/glycemic load, and novel dietary assessment methodologies.
He is a Scientist in the Diabetes Research and Training Center, Center for Aging, Center for Cardiovascular Biology, and Center for Exercise Medicine, and Associate Scientist in the Nutrition Obesity Research Center, Comprehensive Cancer Center, and Minority Health & Research Center at UAB.
N01HC95095 (Shikany) 02/01/1989 – 06/30/2013
Longitudinal Studies of Coronary Heart Disease Risk Factors in Young Adults (CARDIA) - Coordinating Center
Coordinating Center for the four-center CARDIA Study. Goal of the CARDIA Study is to assess coronary artery risk factors in healthy 18-30 year olds. Dr. Shikany serves as the principal investigator of the study’s coordinating center.
U01AR45632 (Shikany) 09/30/1999 – 07/31/2012
Osteoporotic Fractures in Men (MrOS) Renewal - Birmingham
The primary goal of this study is to determine the extent to which fracture risk in older men is related to bone mass, bone geometry, lifestyle factors, biochemical measures, fall propensity, and other variables. Dr. Shikany serves as principal investigator of the Birmingham site.
R01HL053560 (Jacobs) 04/01/2010 – 05/31/2012
(Shikany, subcontract PI)
NIH (NHLBI)/University of Minnesota
Epidemiology Oxidative Stress and Early Atherosclerosis
This ancillary study renewal will collect blood and urine at the CARDIA year 25 exam and conduct biochemical assays related to antioxidants and oxidative damage. Through these measures, we will continue to evaluate the associations of antioxidants and oxidative damage with early/subclinical coronary heart disease and offer possible new means of prevention. Dr. Shikany serves as the principal investigator of the Birmingham field center.
R01DK084997 (Van Den Eeden) 09/15/2010 – 08/31/2014
(Shikany, subcontract PI)
NIH (NIDDK)/Kaiser Foundation Research Institute
Adult Life Predictors of Genitourinary Disorders
The overall objective of this study is to examine how longitudinal changes in selected factors are related to benign genitourinary conditions, including modifiable factors (obesity, physical activity, tobacco and alcohol use, exogenous hormone use, and diet), co-morbidities (diabetes/glucose metabolism, and cardiovascular conditions), and biomarkers (inflammatory markers, lipid levels, endogenous hormone and binding protein levels). We will examine how these factors are related to new onset or change in benign genitourinary conditions. Dr. Shikany serves as the principal investigator of the study’s coordinating center.
R01HL098445 (Carr) 08/01/2010 – 03/31/2015
NIH/Wake Forest University Health Sciences
Longitudinal Changes in Pericardial Adiposity and Subclincal Atherosclerosis
The broad long-term objectives of this study are to reduce the burden of CVD in the US population through increased knowledge of central adiposity and subclinical coronary artery disease that can be translated into prevention activities, development of diagnostic test and monitoring of therapies. The specific aims of this study are focused on elucidating the role of pericardial adipose tissue and its change over 10 years in the development of subclinical atherosclerosis, including specific plaque morphology associated with culprit lesions of myocardial infarction, in middle-aged adults, independent of other risk factors and measures of body size. Dr. Shikany serves as the principal investigator of the study’s coordinating center.
IOTA Chapter, Delta Omega Public Health Honor Society; elected 1992