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Beatriz Yae Hanaoka, MD

Beatriz Yae Hanaoka, MD
Assistant Professor
Department of Medicine 
Division of Clinical Immunology and Rheumatology
Shelby Building, Room 210
1825 University Boulevard
Phone: (205) 996-0843
Fax: (205) 996-6734
Full CV


M.D.: University of Sao Paulo, Brazil, 2005
Internal medicine residency: Cleveland Clinic Foundation, Cleveland, OH, 2005-2008
Rheumatology fellowship: Columbia University, NY, 2008-2010

Research Interests

Body Composition, Skeletal Muscle Dysfunction and Cardiovascular Disease in Rheumatic Diseases

Research Description

Dr. Hanaoka is conducting clinical studies to understand the reasons behind the decline in skeletal muscle function and physical activity in patients with rheumatic diseases, particularly in rheumatoid arthritis (RA). Her research is primary focused on understanding at a mechanistic level the metabolic and physiologic abnormalities of skeletal muscle in RA patients. More specifically, she is investigating if insulin resistance is an underlying cause of skeletal muscle dysfunction in RA patients by conducting clinical trials utilizing an insulin sensitizer. This research is being supported by a K23 NIAMS patient-oriented career development award. Dr. Hanaoka is also conducting additional collaborative studies with her husband, Dr. Prabha Nagareddy (UAB - Nutrition Sciences), and Dr. Andrew Murphy (Baker IDI Institute, Melbourne, Australia) to examine the molecular pathways that contribute to increased cardiovascular disease risk in RA patients.


  1. Prenatal diagnosis of lip and palate cleft: experience of 40 cases. Revista Brasileira de Ginecologia e Obstretricia Prenatal. 2001 Oct; 23: 561-566. Bunduki V, Ruano R, Sapienza AD, Hanaoka BY, Zugaib M.
  2. Prevalence of aneurysms and infrarenal aortic diameter anomalies detected during necropsy”. Jornal Vascular Brasileiro. 2002 Jan; 1: 89-96. Silva ES, Dói A, Hanaoka BY, Takeda FR, Ikeda MH.
  3. Strategies for capacitating physicians in eyelid surgeries using an animal model. Arquivos Brasileiros de Oftalmologia. 2004 May; 67: 437-440. Lopes JF; Buzalaf F; Hanaoka BY; Matayoshi S; Kikuta HS.
  4. C-Reactive Protein and its implications in Systemic Lupus Erythematosus. Acta Rheumatol Port. 2007 Oct-Dec; 32(4): 317-322. De Carvalho JF, Hanaoka B, Szyper-Kravitz M, Shoenfeld Y.
  5. Peripheral Mononeuropathy with Etanercept Use. J Rheumatol. 2008 Jan; 35(1): 182. Hanaoka BY, Libecco J, Rensel M, Hajj-Ali RA.
  6. Implications of glucocorticoid therapy in idiopathic inflammatory myopathies. Nat. Rev. Rheumatol. 2012 Jun 12. Hanaoka BY, Peterson CA, Horbinski C, Crofford LJ. PMID: 22688888
  7. Glucocorticoid effects on skeletal muscle: benefit and risk in patients with autoimmune inflammatory rheumatoid diseases. Expert Review in Clinical Immunology. 2012 Nov; 8(8):695-7. Hanaoka BY, Peterson CA, Crofford LJ. PMID: 23167679
  8. Physical impairment in patients with idiopathic inflammatory myopathies is associated with the American College of Rheumatology functional status measure. Clinical Rheumatology. 2015 Nov; 34(11);1929-37. Hanaoka BY, Cleary LC, Long DE, Srinivas A, Jenkins KA, Bush HM, Starnes CP, Rutledge M, Duan J, Fan Q, Fraser N, Crofford LJ. PMID: 25388646
  9. CT based muscle density predicts muscle function and health-related quality of life in patients with idiopathic inflammatory myopathies. Arthritis Care and Research. Arthritis Care Res. 2015 Jul;67(7):1031-40. Cleary LC, Crofford LJ, Long D, Charnigo R, Clasey J, Beaman F, Jenkins KA, Fraser N, Srinivas A, Dhaon N, Hanaoka BY. PMID: 25623494