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Jeevan Prasain, PhD

Jeevan Prasain, PhD
 
Associate Professor
Department of Pharmacology and Toxicology
1918 18th Street South
McCallum Building Room 456
Birmingham, AL 35294-0005
Phone: (205) 996-2612
Fax: (205) 934-6944
E-mail: jprasain@uab.edu

Education:

M.Sc. in Chemistry, Tribhuvan University, Nepal; Ph.D. in Pharmaceutical Chemistry, Toyama Medical & Pharmaceutical University, Japan; Postdoctoral Fellow in Protein Chemistry, Biotechnology Research Institute, Montreal, Canada; Postdoctoral Fellow in Antibiotics Research, Inst. Phys. Chem Res., Japan; Postdoctoral Fellow in Botanicals/LC-MS at the University of Alabama at Birmingham.

Research/Clinical Interest

Metabolomics/lipidomics, especially delineation of the Cox-independent PG synthesis mechanism, structure identification of signaling lipids/oxidized lipids using untargeted and targeted lipidomics. Bioactive dietary natural products in the prevention of chronic diseases such as diabetes and cancers, their metabolisms, and bioavailability assessment using liquid chromatography tandem mass spectrometry (LC-MS/MS).

Selected Publications

  1. Pier B, Edmonds JW, Wilson L, Arabshahi A, Moore R, Bates GW, Prasain JK, Miller MA
    Comprehensive profiling of prostaglandins in human ovarian follicular fluid using mass spectrometry.
    Prostaglandins Other Lipid Mediat. 2017 Nov 9. pii: S1098-8823(17)30098-9. [doi: 10.1016/j.prostaglandins.2017.11.001] [Epub ahead of print] [PMID: 29129796]
     
  2. Prasain JK, Wilson LS, Arabshahi A, Grubbs C, Barnes S.
    Mass spectrometric evidence for the modification of small molecules in a cobalt-60-irradiated rodent diet.
    J Mass Spectrom. 2017 Aug;52(8):507-516. [doi: 10.1002/jms.3950] Erratum in: J Mass Spectrom. 2017 Oct;52(10 ):707.
    [ PMID: 28544323]
     
  3. Shamik Das, William P. Jackson, Jeevan K. Prasain, Ann Hanna, Sarah K. Bailey, J. Allan Tucker, Sejong Bae, Landon S. Wilson, Rajeev S. Samant, Stephen Barnes & Lalita A. Shevde
    Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling.
    Scientific Reports 7, Article number: 40773 [doi:10.1038/srep40773]