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C. Roger White, PhD

C. Roger White, PhD
 		 Professor
Department of Medicine
Division of Cardiovascular Disease
Zeigler Research Building, Room 1046
703 19th Street South
Birmingham, Alabama 35294-0007
Email Address: crwhite@uab.edu   
Office Phone:   (205) 934-5951
Web Site


Research Interests

  1. Oxidant stress and endothelial dysfunction
  2. Mechanisms by which high density lipoprotein (HDL) modulates vascular function under acute and chronic inflammatory conditions
  3. Relationships between circulating lipoproteins, pro-oxidant enzyme expression/function and endothelial function 
  4. Novel, synthetic apolipoprotein (apo) mimetic peptides that mimic effects of endogenous HDL

Training:

  1. Postdoc Fellowship: Vascular Biology & Hypertension Training Program, UAB
  2. Doctor of Philosophy: University of Illinois at Urbana-Champaign
  3. Master Degree: Lake Forest College, Illinois

Selected Journal Articles

  1. Dai L, Datta G, Zhang Z, Gupta H, Patel R, Honavar J, Modi S, Wyss JM, Palgunachari M, Anantharamaiah GM, White CR. The apolipoprotein A-I mimetic peptide 4F prevents defects in vascular function in endotoxemic rats. J Lipid Res. 2010 Sep;51(9):2695-705. Epub 2010 May 22.
    PMID: 20495214
  2. Khoo NK, White CR, Pozzo-Miller L, Zhou F, Constance C, Inoue T, Patel RP, Parks DA. Dietary flavonoid quercetin stimulates vasorelaxation in aortic vessels. Free Radic Biol Med. 2010 Aug 1;49(3):339-47. Epub 2010 Apr 25.
    PMID: 20423726
  3. Samal A, Honovar J, White CR, Patel RP. A Potential for chlorine gas-induced injury in the extrapulmonary vasculature. Proc Am Thorac Soc. 2010 Jul;7(4):290-3. Review.
    PMID: 20601634
  4. Smythies LE, White CR, Maheshwari A, Palgunachari MN, Anantharamaiah GM, Chaddha M, Kurundkar AR, Datta G. Apolipoprotein A-I mimetic 4F alters the function of human monocyte-derived macrophages. Am J Physiol Cell Physiol. 2010 Jun;298(6):C1538-48. Epub 2010 Mar 10.
    PMID: 20219948
  5. Datta G, Chaddha M, Handattu SP, Palgunachari MN, Nayyar G, Garber DW, Gupta H, White CR, Anantharamaiah GM. ApoE mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL paraoxonase activity. Adv Exp Med Biol. 2010;660:1-4.
    PMID: 20221865